Prevalence and risk factors of human pegivirus type 1 infection in hematopoietic stem cell transplantation patients

•The prevalence of human pegivirus type 1 (HPgV-1) in hematopoietic stem cell transplantation (HSCT) patients is 18.6%.•The prevalence of HPgV-1 is higher in HSCT patients than in healthy blood donors.•The predominant genotype of HPgV-1 in HSCT patients is genotype 3.•More transfusions were given to...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of infectious diseases 2019-08, Vol.85, p.111-113
Main Authors:	Li, Zhanjia, Li, Yuhang, Liang, Yuying, Hu, Liangding, Chen, Shuiping
Format:	Article
Language:	eng
Subjects:	Blood transfusion Genotype Hematopoietic stem cell transplantation Human pegivirus Prevalence
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	•The prevalence of human pegivirus type 1 (HPgV-1) in hematopoietic stem cell transplantation (HSCT) patients is 18.6%.•The prevalence of HPgV-1 is higher in HSCT patients than in healthy blood donors.•The predominant genotype of HPgV-1 in HSCT patients is genotype 3.•More transfusions were given to HSCT patients with RNA test conversions (negative to positive) than to those without this conversion. To investigate the prevalence, risk factors, and genotypes of human pegivirus type 1 (HPgV-1) in hematopoietic stem cell transplantation (HSCT) patients. One hundred and eighty-eight HSCT patients and 694 healthy blood donors were investigated retrospectively, including their demographic information and HPgV-1 infection status. When compared with healthy blood donors, a significantly higher HPgV-1 prevalence (18.6% vs. 2.3%) and a high risk of HPgV-1 infection (odds ratio 9.7) were observed in HSCT patients (p
ISSN:	1201-9712 1878-3511