Association of dry eye disease with psychiatric or neurological disorders in elderly patients

Dry eye disease (DED) is a common disease that can impair quality of life significantly. Its prevalence increases with advancing age, and the economic burden of the disease on both a patient and the society is increasing with elongation of life expectancy. The diagnosis and treatment of DED are ofte...

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Bibliographic Details
Published in:	Clinical interventions in aging 2017-01, Vol.12, p.785-792
Main Authors:	Han, Sang Beom, Yang, Hee Kyung, Hyon, Joon Young, Wee, Won Ryang
Format:	Article
Language:	eng
Subjects:	Age Aged Aged patients Anxiety Anxiety Disorders - epidemiology Care and treatment Chronic Pain - epidemiology Complications and side effects Cornea Cross-Sectional Studies Depression Depressive Disorder - epidemiology Development and progression Drug delivery systems Dry eye Disease Dry eye syndromes Dry Eye Syndromes - epidemiology Elderly patients Eye diseases Female Hospitals Humans Male Mental depression Mental disorders Mental Disorders - epidemiology Middle Aged Migraine Nervous system Nervous system diseases Nervous System Diseases - epidemiology Neurological Disorder Neurological disorders Neuropathic Pain Older people Pain Pathogenesis Patients Population Post traumatic stress disorder Prevalence Psychiatric Disorders Quality of Life Questionnaires Review Risk Factors Sleep Disorder Surveys and Questionnaires Womens health
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Summary:	Dry eye disease (DED) is a common disease that can impair quality of life significantly. Its prevalence increases with advancing age, and the economic burden of the disease on both a patient and the society is increasing with elongation of life expectancy. The diagnosis and treatment of DED are often difficult due to the discordance between symptoms and signs of the disease. Recent studies have suggested the role of neurological or psychological factors in the development of dry eye symptoms and discrepancy of the symptoms and signs, particularly in elderly patients. In this review, the authors discuss the association of DED with various psychiatric and neurological disorders. In addition to psychiatric conditions, including depression, anxiety, stress, posttraumatic stress disorder and sleep disorders, medications for the psychiatric disorders have association with DED. Neurological disorders, such as neuropathic pain, chronic pain syndrome, peripheral neuropathy and several central nervous system disorders, are related to DED. Treatment of DED, combined with psychiatric or neurological disorders, is also discussed. Attention should be paid to the DED patients with discordant symptoms and signs, and unsatisfactory response to conventional treatment for associated psychiatric or neurological disorders, as well as an integrated treatment approach, could be helpful for these patients.
ISSN:	1178-1998 1176-9092 1178-1998