Organ Donation after Damage Control Strategy in Trauma Patients: Experience from First Level Trauma Center in Italy

Organ Donation after Damage Control Strategy in Trauma Patients: Experience from First Level Trauma Center in Italy

Organ donation (OD) remains the only therapeutic option for end-stage disease in some cases. Unfortunately, the gap between donors and recipients is still substantial. Trauma patients represent a potential yet underestimated pool of organ donors. In this article, we present our data on OD after dama...

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Bibliographic Details
Published in:Life (Basel, Switzerland) Switzerland), 2022-01, Vol.12 (2), p.214
Main Authors: Altomare, Michele, Bekhor, Shir Sara, Cioffi, Stefano Piero Bernardo, Sacchi, Marco, Renzi, Federica, Spota, Andrea, Bini, Roberto, Ambrogi, Federico, Pozzi, Federico, Chieregato, Arturo, Chiara, Osvaldo, Cimbanassi, Stefania
Format: Article
Language:eng
Subjects:
Blood & organ donations
Damage
damage control
damage control surgery
Donors
Heart
Hormone replacement therapy
Injuries
Intensive care
Kidneys
Liver
Lungs
Medical imaging
Missing data
organ donation
Organs
Patients
Subgroups
Transplantation
Transplants & implants
Trauma
Trauma centers
trauma donors
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Summary:Organ donation (OD) remains the only therapeutic option for end-stage disease in some cases. Unfortunately, the gap between donors and recipients is still substantial. Trauma patients represent a potential yet underestimated pool of organ donors. In this article, we present our data on OD after damage control strategy (DCS). A retrospective, observational cohort study was conducted through a complete revision of data of consecutive adult trauma patients (>18 years old) who underwent OD after DCS between January 2018 and May 2021. Four subgroups were created [Liver (Li), Lungs (Lu), Heart (H), Kidneys (K)] to compare variables between those who donated the organ of interest and those who did not. Thirty-six patients underwent OD after DCS. Six patients (16.7%) were excluded: 2(5.6%) for missing data about admission; 4(11.1%) didn't receive DCS. Mean ISS was 47.2 (SD ± 17.4). Number of donated organs was 113 with an organs/patient ratio of 3.8. The functional response rate was 91.2%. Ten organs (8.8%) had primary nonfunction after transplantation: 2/15 hearts (13.3%), 1/28 livers (3.6%), 4/53 kidneys (7.5%) and 3/5 pancreases (60%). No lung primary nonfunction were registered. Complete results of subgroup analysis are reported in supplementary materials. Organ donation should be considered a possible outcome in any trauma patient. Aggressive damage control strategy doesn't affect the functional response rate of transplanted organs.
ISSN:2075-1729
2075-1729