Vaccination of chickens against coccidiosis ameliorates drug resistance in commercial poultry production
[Display omitted] •Resistance has developed to all those drugs used to control coccidiosis in chickens.•Some vaccines contain strains of Eimeria that are sensitive to drugs.•Such strains may replace drug resistant strains in commercial poultry houses.•A production cycle involving chemotherapy follow...
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| Published in: | International journal for parasitology -- drugs and drug resistance 2014-12, Vol.4 (3), p.214-217 |
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| Main Authors: | , |
| Format: | Article |
| Language: | eng |
| Subjects: | |
| Online Access: | Get full text |
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| Summary: | [Display omitted]
•Resistance has developed to all those drugs used to control coccidiosis in chickens.•Some vaccines contain strains of Eimeria that are sensitive to drugs.•Such strains may replace drug resistant strains in commercial poultry houses.•A production cycle involving chemotherapy followed by vaccination is presented.•Such a yearly cycle may restore sensitivity to anticoccidial drugs.
Drug resistance is a problem wherever livestock are raised under intensive conditions and drugs are used to combat parasitic infections. This is particularly true for the anticoccidial agents used for the prevention of coccidiosis caused by protozoa of the apicomplexan genus Eimeria in poultry. Resistance has been documented for all the dozen or so drugs approved for use in chickens and varying levels of resistance is present for those currently employed. A possible solution may be the introduction of drug-sensitive parasites into the houses where poultry are raised so that they may replace such drug-resistant organisms. This can be achieved by utilizing live vaccines that contain strains of Eimeria that were isolated before most anticoccidial compounds were introduced. Such strains are inherently drug-sensitive. Practical proposals to achieve this objective involve the alternation of vaccination with medication (known as rotation programs) in successive flocks reared in the same poultry house. A proposal for a yearly broiler production cycle involving chemotherapy and vaccination is presented. There are few, if any, examples in veterinary parasitology where it has proved possible to restore sensitivity to drugs used to control a widespread parasite. Further research is necessary to ascertain whether this can result in sustainable and long-term control of Eimeria infections in poultry. |
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| ISSN: | 2211-3207 2211-3207 |