Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus

In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Furth...

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Bibliographic Details
Published in:	International journal of nanomedicine 2010-01, Vol.5 (default), p.277-283
Main Authors:	Tran, Nhiem, Mir, Aparna, Mallik, Dhriti, Sinha, Arvind, Nayar, Suprabha, Webster, Thomas J
Format:	Article
Language:	eng
Subjects:	Anti-Bacterial Agents - administration & dosage bactericide Cell Survival - drug effects Dose-Response Relationship, Drug drug delivery Ferric Compounds - administration & dosage magnetic nanoparticles Materials Testing Nanoparticles Nanoparticles - administration & dosage nanotechnology Original Research Particle Size Pathogens Polyvinyl alcohol Staphylococcus aureus - drug effects
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Summary:	In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at the highest concentration (3 mg/mL) at all time points.
ISSN:	1178-2013 1176-9114 1178-2013