Biological Diagnosis of Depression: A Biomarker Panel from Several Nonspecial Indicators Instead of the Specific Biomarker(s)

Biological Diagnosis of Depression: A Biomarker Panel from Several Nonspecial Indicators Instead of the Specific Biomarker(s)

It is a consensus that the diagnosis efficiency of depression is rather low in clinic. The traditional way of diagnosing depression by symptomatology is flawed. Recent years, a growing body of evidence has underlined the importance of physiological indicators in the diagnosis of depression. However,...

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Bibliographic Details
Published in:Neuropsychiatric disease and treatment 2022-01, Vol.18, p.3067-3071
Main Authors: Li, Jia-Mei, Jiang, Chun-Lei
Format: Article
Language:eng
Subjects:
Algorithms
Big Data
biological diagnosis
Biological markers
biomarker
Biomarkers
Clinical medicine
Cytokines
depression
Depression, Mental
Diagnosis
Disease
Gene expression
Hypothesis
Medical diagnosis
Mental depression
Neurotrophic factors
nonspecial indicator
panel
Pathogenesis
Physiology, Pathological
Psychiatric research
Thyroid gland
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Summary:It is a consensus that the diagnosis efficiency of depression is rather low in clinic. The traditional way of diagnosing depression by symptomatology is flawed. Recent years, a growing body of evidence has underlined the importance of physiological indicators in the diagnosis of depression. However, the diagnosis of depression is difficult to be like some common clinical diseases, which have clear physiological indicators. A single physiological index provides limited information to clinicians and is of little help in the diagnosis of depression. Thus, it is more rational and practical to diagnose depression with a biomarker panel, which covers a few non-specific indicators, such as hormones, cytokines, and neurotrophins. This open review suggested that biomarker panel had a bright future in creating a new model of depression diagnosis or at least providing a reference to the existing depression criteria. The viewpoint is also the future of other psychiatric diagnosis.
ISSN:1176-6328
1178-2021
1178-2021