Antiulcer Agents: From Plant Extracts to Phytochemicals in Healing Promotion

In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemical...

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Bibliographic Details
Published in:	Molecules (Basel, Switzerland) Switzerland), 2018-07, Vol.23 (7), p.1751
Main Authors:	Sharifi-Rad, Mehdi, Fokou, Patrick Valere Tsouh, Sharopov, Farukh, Martorell, Miquel, Ademiluyi, Adedayo Oluwaseun, Rajkovic, Jovana, Salehi, Bahare, Martins, Natália, Iriti, Marcello, Sharifi-Rad, Javad
Format:	Article
Language:	eng
Subjects:	Animals bioactive phytochemicals gastric cancer Helicobacter Infections - drug therapy Helicobacter pylori Herbal medicine herbal remedies Humans In vivo methods and tests peptic ulcer Peptic Ulcer - drug therapy Peptic Ulcer - microbiology Phytochemicals Plant extracts Plant Extracts - chemistry Plant Extracts - therapeutic use Product safety Review traditional healing systems
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Summary:	In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.
ISSN:	1420-3049 1420-3049