Serous macular detachment, yellow macular deposits, and prominent middle limiting membrane in multiple myeloma

Bone marrow-derived multiple myeloma is a type of plasma cell tumor that may be associated with ocular complications. A 52-year-old male patient was admitted to our eye clinic with the complaint of sudden visual loss and a visual acuity of 20/50 in the right eye and 20/800 in the left eye. Fundus ex...

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Bibliographic Details
Published in:Therapeutics and clinical risk management 2015-01, Vol.11 (default), p.683-689
Main Authors: Dogan, Berna, Erol, Muhammet Kazim, Toslak, Devrim, Coban, Deniz Turgut, Bulut, Mehmet, Cengiz, Ayse, Sari, Esin Sogutlu
Format: Article
Language:English
Subjects:
Blood
Care and treatment
Case Report
Case reports
Case studies
Complications and side effects
Cysts
Development and progression
Hematology
Medical imaging
Multiple myeloma
Patients
prominent middle limiting membrane
Retina
serous macular detachment
Vision disorders
yellow macular deposit
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Summary:Bone marrow-derived multiple myeloma is a type of plasma cell tumor that may be associated with ocular complications. A 52-year-old male patient was admitted to our eye clinic with the complaint of sudden visual loss and a visual acuity of 20/50 in the right eye and 20/800 in the left eye. Fundus examination revealed common flame-shaped hemorrhages, venous dilatation and tortuosity, Roth spots, serous macular detachment, and yellow macular deposits in both eyes. Evaluation with fundus fluorescein angiography, fundus autofluorescence, and spectral-domain optical coherence tomography resulted in suspicion of hyperviscosity retinopathy and referral to the hematology clinic. After hematology consultation confirmed a diagnosis of multiple myeloma, chemotherapy and plasmapheresis were initiated. Four months after presentation, best-corrected visual acuity was 20/20 in both eyes and improvement in hyperviscosity retinopathy, serous macular detachment, and yellow macular deposits was observed.
ISSN:1176-6336
1178-203X
1178-203X
DOI:10.2147/TCRM.S79232