Triglyceride glucose index for the detection of asymptomatic coronary artery stenosis in patients with type 2 diabetes

Triglyceride glucose index for the detection of asymptomatic coronary artery stenosis in patients with type 2 diabetes

Triglyceride Glucose (TyG) index has been associated with an increased risk in cardiovascular events. Silent coronary disease is common in patients with type 2 diabetes. In Vietnam, a low-middle income country, the burden of cardiovascular disease is growing simultaneously with the epidemiologic tra...

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Bibliographic Details
Published in:Cardiovascular diabetology 2020-09, Vol.19 (1), p.137-137, Article 137
Main Authors: Thai, Pham Viet, Tien, Hoang Anh, Van Minh, Huynh, Valensi, Paul
Format: Article
Language:eng
Subjects:
Angiography
Cardiovascular disease
Cardiovascular diseases
Cholesterol
Computed tomography
Coronary artery
Coronary artery disease
Coronary computed tomography angiography
Diabetes mellitus (non-insulin dependent)
Epidemiology
Glucose
Heart diseases
High density lipoprotein
Insulin
Insulin resistance
Low density lipoprotein
Medical imaging
Metabolic disorders
Metabolic syndrome
Original Investigation
Physical activity
Risk factors
Stenosis
Tomography
Triglyceride glucose index
Triglycerides
Type 2 diabetes
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Summary:Triglyceride Glucose (TyG) index has been associated with an increased risk in cardiovascular events. Silent coronary disease is common in patients with type 2 diabetes. In Vietnam, a low-middle income country, the burden of cardiovascular disease is growing simultaneously with the epidemiologic transition. Our aim was to assess the prevalence of coronary stenoses (CS) in patients with type 2 diabetes and no history or symptom of cardiovascular disease and to investigate the association between TyG index and cardiovascular risk factors and both the presence and severity of CS. Futhermore, we assessed the value of TyG index in predicting subclinical CS. This was a cross-sectional observational study. We recruited 166 patients at Ninh Thuan General Hospital, Vietnam. TyG index and HOMA-IR were calculated, and a coronary computed tomography angiography (CCTA) was performed. The population was classified according to tertiles of TyG index. The highest TyG values were associated with higher BMI, waist circumference, total cholesterol, LDL-cholesterol, triglycerides, plasma glucose, HbA1c levels and HOMA-IR, lower HDL-cholesterol, a higher incidence of metabolic syndrome and less frequent physical activity (p 
ISSN:1475-2840
1475-2840