Virtual reality-based therapy improves balance and reduces fear of falling in patients with multiple sclerosis. a systematic review and meta-analysis of randomized controlled trials

This study aims to conduct a meta-analysis to assess the effect of virtual reality-based therapy (VRBT) on balance dimensions and fear of falling in patients with multiple sclerosis (PwMS). Secondarily, to determine the most recommendable dose of VRBT to improve balance. PubMed Medline, Web of Scien...

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Published in:	Journal of neuroengineering and rehabilitation 2023-04, Vol.20 (1), p.42-42, Article 42
Main Authors:	Cortés-Pérez, Irene, Osuna-Pérez, María Catalina, Montoro-Cárdenas, Desirée, Lomas-Vega, Rafael, Obrero-Gaitán, Esteban, Nieto-Escamez, Francisco Antonio
Format:	Article
Language:	eng
Subjects:	Accidental Falls - prevention & control Analysis Balance Care and treatment Clinical trials Computer applications Diagnosis Disability Falls Fear Fear of falling Gait Gait speed Health aspects Humans Meta-analysis Multiple Sclerosis Patients Physical therapy Physical Therapy Modalities Postural balance Postural control Posture Quality of life Randomized Controlled Trials as Topic Rehabilitation Review Software Systematic review Virtual Reality
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Summary:	This study aims to conduct a meta-analysis to assess the effect of virtual reality-based therapy (VRBT) on balance dimensions and fear of falling in patients with multiple sclerosis (PwMS). Secondarily, to determine the most recommendable dose of VRBT to improve balance. PubMed Medline, Web of Science, Scopus, CINAHL and PEDro were screened, without publication date restrictions, until September 30th, 2021. Randomized controlled trials (RCTs) comparing the effectiveness of VRBT against other interventions in PwMS were included. Functional and dynamic balance, confidence of balance, postural control in posturography, fear of falling and gait speed were the variables assessed. A meta-analysis was performed by pooling the Cohen's standardized mean difference (SMD) with 95% confidence interval (95% CI) using Comprehensive Meta-Analysis 3.0. Nineteen RCTs, reporting 858 PwMS, were included. Our findings reported that VRBT is effective in improving functional balance (SMD = 0.8; 95%CI 0.47 to 1.14; p
ISSN:	1743-0003 1743-0003