Clinical and Histopathological Features of Scleroderma-like Disorders: An Update

Scleroderma-like disorders include a set of entities involving cutis, subcutis and, sometimes, even muscular tissue, caused by several pathogenetic mechanisms responsible for different clinical–pathological pictures. The absence of antinuclear antibodies (ANA), Raynaud’s phenomenon and capillaroscop...

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Bibliographic Details
Published in:	Medicina (Kaunas, Lithuania) Lithuania), 2021-11, Vol.57 (11), p.1275
Main Authors:	Foti, Rosario, De Pasquale, Rocco, Dal Bosco, Ylenia, Visalli, Elisa, Amato, Giorgio, Gangemi, Pietro, Foti, Riccardo, Ramondetta, Alice
Format:	Article
Language:	eng
Subjects:	Atrophy Biopsy Chronic illnesses Collagen cutaneous sclerosis Etiology Fibroblasts Graft versus host disease Histology Laboratories Review scleredema Scleroderma scleroderma-like sclerodermiform mucinosis
Online Access:	Get full text
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Summary:	Scleroderma-like disorders include a set of entities involving cutis, subcutis and, sometimes, even muscular tissue, caused by several pathogenetic mechanisms responsible for different clinical–pathological pictures. The absence of antinuclear antibodies (ANA), Raynaud’s phenomenon and capillaroscopic anomalies constitutes an important element of differential diagnosis with systemic sclerosis. When scleroderma can be excluded, on the basis of the main body sites, clinical evolution, any associated pathological conditions and specific histological features, it is possible to make a correct diagnosis.
ISSN:	1648-9144 1010-660X 1648-9144