Whole-Transcriptome RNA Sequencing Reveals Significant Differentially Expressed mRNAs, miRNAs, and lncRNAs and Related Regulating Biological Pathways in the Peripheral Blood of COVID-19 Patients

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in China and currently worldwide dispersed, resulting in the coronavirus disease 2019 (COVID-19) pandemic. Notably, COVID-19 is characterized by systemic inflammation. However, the potential mechanisms of the “cyto...

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Bibliographic Details

Published in:	Mediators of inflammation 2021, Vol.2021, p.6635925-22
Main Authors:	Li, Cai-xia, Chen, Jian, Lv, Shu-kai, Li, Jin-hui, Li, Lei-lei, Hu, Xiao
Format:	Article
Language:	eng
Subjects:	Adult Aged AKT1 protein Antigen presentation Antigen processing Case-Control Studies Cell activation China Comparative analysis Coronaviridae Coronaviruses COVID-19 COVID-19 - blood COVID-19 - complications COVID-19 - genetics Cytokine Release Syndrome - blood Cytokine Release Syndrome - etiology Cytokine Release Syndrome - genetics Cytokine storm Cytokines Cytokines - biosynthesis Cytokines - genetics Cytotoxicity Development and progression Epidemics Fc receptors Female Gene Expression Genes Glycogen Health aspects Humans Inflammation Inflammation Mediators - blood Leukocyte migration Lymphocytes T Male Medical research Medicine, Experimental Messenger RNA MicroRNA MicroRNAs MicroRNAs - blood MicroRNAs - genetics Middle Aged Middle East respiratory syndrome miRNA Pandemics Peripheral blood Protein interaction Protein Interaction Maps - genetics Protein-protein interactions RNA - blood RNA - genetics RNA sequencing RNA, Long Noncoding - blood RNA, Long Noncoding - genetics RNA, Messenger - blood RNA, Messenger - genetics SARS-CoV-2 Sequence Analysis, RNA Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Signal Transduction Stat3 protein T cells TLR2 protein Toll-like receptors Transcriptomes Whole Exome Sequencing Young Adult
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