Caffeic Acid-layered Double Hydroxide Hybrid: A New Raw Material for Cosmetic Applications

Bioactive ingredients from natural sources possess well-known positive effects in cosmetic applications. Among them, phenolic acids have emerged with very interesting potential. Caffeic acid (CAF) is one of the most promising active compounds because it possess antioxidant, anti-inflammatory, antitu...

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Bibliographic Details
Published in:	Cosmetics (Basel) 2018-09, Vol.5 (3), p.51
Main Authors:	Bastianini, Maria, Faffa, Caterina, Sisani, Michele, Petracci, Annarita
Format:	Article
Language:	eng
Subjects:	Acids anti-wrinkle Antioxidants Bioavailability Biocompatibility Caffeic acid Chemistry Clay Cosmetics Ethanol Gene expression hybrids Inflammation layered double hydroxides Minerals Oxidation Phenolic acids Photodegradation raw material Toxicity
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Summary:	Bioactive ingredients from natural sources possess well-known positive effects in cosmetic applications. Among them, phenolic acids have emerged with very interesting potential. Caffeic acid (CAF) is one of the most promising active compounds because it possess antioxidant, anti-inflammatory, antitumoral and anti-wrinkle effects. In order to increase its local bioavailability in topical applications, the vehiculation of caffeic acid can lead to a new raw material of cosmetic interest. For this purpose, clay minerals possess excellent properties, such as low or null toxicity and good biocompatibility. Clays are able to host a wide range of active ingredients in the interlayer region, using a green process known as intercalation reaction. The hosting of cosmetic actives into the layered structure of anionic clays allows the preparation of new materials with enhanced stability towards oxidation and photodegradation, better local bioavailability, and easier workability. In this paper, the successful vehiculation of caffeic acid into anionic clay is presented. The obtained hybrid is very promising for the cosmetic market because of its higher bioavailability and prolonged antioxidant activity.
ISSN:	2079-9284 2079-9284