The Structure-Activity Relationship of the Antioxidant Peptides from Natural Proteins

Peptides derived from dietary proteins, have been reported to display significant antioxidant activity, which may exert notably beneficial effects in promoting human health and in food processing. Recently, much research has focused on the generation, separation, purification and identification of n...

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Bibliographic Details
Published in:	Molecules 2016-01, Vol.21 (1), p.72-72
Main Authors:	Zou, Tang-Bin, He, Tai-Ping, Li, Hua-Bin, Tang, Huan-Wen, Xia, En-Qin
Format:	Article
Language:	eng
Subjects:	Amino Acid Sequence Amino Acids - chemistry Amino Acids - metabolism Amino Acids - pharmacology antioxidant peptides Antioxidants - chemistry Antioxidants - metabolism Antioxidants - pharmacology Biological Products - administration & dosage Dietary Proteins - administration & dosage Dietary Proteins - metabolism Dietary Proteins - pharmacology Humans Hydrophobic and Hydrophilic Interactions Molecular Sequence Data Peptide Fragments - chemistry Peptide Fragments - metabolism Peptide Fragments - pharmacology proteins Proteolysis Quantitative Structure-Activity Relationship Reactive Oxygen Species - antagonists & inhibitors Reactive Oxygen Species - metabolism Review Static Electricity structure-activity relationship
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Summary:	Peptides derived from dietary proteins, have been reported to display significant antioxidant activity, which may exert notably beneficial effects in promoting human health and in food processing. Recently, much research has focused on the generation, separation, purification and identification of novel peptides from various protein sources. Some researchers have tried to discover the structural characteristics of antioxidant peptides in order to lessen or avoid the tedious and aimless work involving the ongoing generated peptide preparation schemes. This review aims to summarize the current knowledge on the relationship between the structural features of peptides and their antioxidant activities. The relationship between the structure of the precursor proteins and their abilities to release antioxidant fragments will also be summarized and inferred. The preparation methods and antioxidant capacity evaluation assays of peptides and a prediction scheme of quantitative structure-activity relationship (QSAR) will also be pointed out and discussed.
ISSN:	1420-3049 1420-3049