Impact of Morphine Treatment on Infarct Size and Reperfusion Injury in Acute Reperfused ST-Elevation Myocardial Infarction

Current evidence regarding the effect of intravenous morphine administration on reperfusion injury and/or cardioprotection in patients with myocardial infarction is conflicting. The aim of this study was to evaluate the impact of morphine administration, on infarct size and reperfusion injury assess...

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Bibliographic Details
Published in:	Journal of clinical medicine 2020-03, Vol.9 (3), p.735
Main Authors:	Eitel, Ingo, Wang, Juan, Stiermaier, Thomas, Fuernau, Georg, Feistritzer, Hans-Josef, Joost, Alexander, Jobs, Alexander, Meusel, Moritz, Blodau, Christian, Desch, Steffen, de Waha-Thiele, Suzanne, Langer, Harald, Thiele, Holger
Format:	Article
Language:	eng
Subjects:	Acute coronary syndromes Age cmr Diabetes Ejection fraction Heart attacks Hypertension infarct size Laboratories Morphine Patients Regression analysis reperfusion st-elevation myocardial infarction Statistical analysis
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Summary:	Current evidence regarding the effect of intravenous morphine administration on reperfusion injury and/or cardioprotection in patients with myocardial infarction is conflicting. The aim of this study was to evaluate the impact of morphine administration, on infarct size and reperfusion injury assessed by cardiac magnetic resonance imaging (CMR) in a large multicenter ST-elevation myocardial infarction (STEMI) population. In total, 734 STEMI patients reperfused by primary percutaneous coronary intervention
ISSN:	2077-0383 2077-0383