Risk factors on admission associated with hospital length of stay in patients with COVID-19: a retrospective cohort study

Risk factors on admission associated with hospital length of stay in patients with COVID-19: a retrospective cohort study

Treating patients with COVID-19 is expensive, thus it is essential to identify factors on admission associated with hospital length of stay (LOS) and provide a risk assessment for clinical treatment. To address this, we conduct a retrospective study, which involved patients with laboratory-confirmed...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2021-03, Vol.11 (1), p.7310-7310, Article 7310
Main Authors: Guo, Anping, Lu, Jin, Tan, Haizhu, Kuang, Zejian, Luo, Ying, Yang, Tian, Xu, Junlan, Yu, Jishuang, Wen, Canhong, Shen, Aizong
Format: Article
Language:eng
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
China
Cohort analysis
Comorbidity
Coronaviruses
COVID-19
COVID-19 - epidemiology
COVID-19 - etiology
Creatinine
Creatinine - blood
Female
Fever
Fever - virology
Hospitalization
Humans
Kidneys
Laboratories
Length of stay
Length of Stay - statistics & numerical data
Liver diseases
Male
Medical records
Middle Aged
Multivariate Analysis
Patients
Renal Insufficiency, Chronic - epidemiology
Retrospective Studies
Risk assessment
Risk factors
Sex
Young Adult
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Treating patients with COVID-19 is expensive, thus it is essential to identify factors on admission associated with hospital length of stay (LOS) and provide a risk assessment for clinical treatment. To address this, we conduct a retrospective study, which involved patients with laboratory-confirmed COVID-19 infection in Hefei, China and being discharged between January 20 2020 and March 16 2020. Demographic information, clinical treatment, and laboratory data for the participants were extracted from medical records. A prolonged LOS was defined as equal to or greater than the median length of hospitable stay. The median LOS for the 75 patients was 17 days (IQR 13-22). We used univariable and multivariable logistic regressions to explore the risk factors associated with a prolonged hospital LOS. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were estimated. The median age of the 75 patients was 47 years. Approximately 75% of the patients had mild or general disease. The univariate logistic regression model showed that female sex and having a fever on admission were significantly associated with longer duration of hospitalization. The multivariate logistic regression model enhances these associations. Odds of a prolonged LOS were associated with male sex (aOR 0.19, 95% CI 0.05-0.63, p = 0.01), having fever on admission (aOR 8.27, 95% CI 1.47-72.16, p = 0.028) and pre-existing chronic kidney or liver disease (aOR 13.73 95% CI 1.95-145.4, p = 0.015) as well as each 1-unit increase in creatinine level (aOR 0.94, 95% CI 0.9-0.98, p = 0.007). We also found that a prolonged LOS was associated with increased creatinine levels in patients with chronic kidney or liver disease (p 
ISSN:2045-2322
2045-2322