Determining the minimally important difference in quadriceps strength in individuals with COPD using a fixed dynamometer

Measurement of quadriceps muscular force is recommended in individuals with COPD, notably during a pulmonary rehabilitation program (PRP). However, the tools used to measure quadriceps maximal voluntary contraction (QMVC) and the clinical relevance of the results, as well as their interpretation for...

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Bibliographic Details
Published in:	International journal of chronic obstructive pulmonary disease 2018-01, Vol.13, p.2685-2693
Main Authors:	Vaidya, Trija, Beaumont, Marc, de Bisschop, Claire, Bazerque, Lucie, Le Blanc, Camille, Vincent, Anne, Ouksel, Hakima, Chambellan, Arnaud
Format:	Article
Language:	eng
Subjects:	Analysis Anxiety Chronic illnesses Chronic obstructive lung disease Chronic obstructive pulmonary disease COPD Depression (Mood disorder) dynamometer Dyspnea Exercise Female Fitness training programs Forced Expiratory Volume France Humans Knee Life Sciences Lung diseases, Obstructive Male Medical research Middle Aged Muscle Strength - physiology Muscle Strength Dynamometer muscular dysfunction Original Research Patients Physical fitness Pulmonary Disease, Chronic Obstructive - physiopathology Pulmonary Disease, Chronic Obstructive - rehabilitation pulmonary rehabilitation QMVC Quadriceps Muscle - physiology Quality of Life Rehabilitation Surveys and Questionnaires Values Variance analysis
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Summary:	Measurement of quadriceps muscular force is recommended in individuals with COPD, notably during a pulmonary rehabilitation program (PRP). However, the tools used to measure quadriceps maximal voluntary contraction (QMVC) and the clinical relevance of the results, as well as their interpretation for a given patient, remain a matter of debate. The objective of this study was to estimate the minimally important difference (MID) of QMVC using a fixed dynamometer in individuals with COPD undergoing a PRP. Individuals with COPD undergoing a PRP were included in this study. QMVC was measured using a dynamometer (MicroFET2) fixed on a rigid support according to a standard-ized methodology. Exercise capacity was measured by 6-minute walk distance (6MWD) and evaluation of quality of life with St George's respiratory questionnaire (SGRQ) and Hospital Anxiety and Depression Scale (HADS) total scores. All measures were obtained at baseline and the end of the PRP. The MID was calculated using distribution-based methods. A total of 157 individuals with COPD (age 62.9±9.0 years, forced expiratory volume in 1 second 47.3%±18.6% predicted) were included in this study. At the end of the PRP, the patients had improved their quadriceps force significantly by 8.9±15.6 Nm (
ISSN:	1178-2005 1176-9106 1178-2005