The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes

Clinical data suggest that BMI and gestational weight gain (GWG) are strongly interconnected phenotypes; however, the genetic basis of the latter is rather unclear. Here we aim to find genes and genetic variants which influence BMI and/or GWG. We have genotyped 316 type 1 diabetics using Illumina In...

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Bibliographic Details

Published in:	Molecular medicine (Cambridge, Mass.) Mass.), 2021-01, Vol.27 (1), p.6-6, Article 6
Main Authors:	Ludwig-Słomczyńska, Agnieszka H, Seweryn, Michał T, Kapusta, Przemysław, Pitera, Ewelina, Mantaj, Urszula, Cyganek, Katarzyna, Gutaj, Paweł, Dobrucka, Łucja, Wender-Ożegowska, Ewa, Małecki, Maciej T, Wołkow, Paweł P
Format:	Article
Language:	eng
Subjects:	Adult Association analysis BMI Body Mass Index Chemokine CCL24 - genetics Data processing Diabetes Diabetes Mellitus, Type 1 - genetics Exome Sequencing Female Gene expression Gene Expression Profiling - methods Gene loci Genetic Association Studies Genotype & phenotype Gestational age Gestational weight gain (GWG) Gestational Weight Gain - genetics Gynecology High-Throughput Nucleotide Sequencing Humans Hyperglycemia Insulin Metabolism Obesity Obstetrics Polymorphism, Single Nucleotide Population Preeclampsia Pregnancy Sialoglycoproteins - genetics Stillbirth Transcriptomic-wide association study (TWAS) Womens health
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