Protective Effects of Lactoferrin against SARS-CoV-2 Infection In Vitro

SARS-CoV-2 is a newly emerging virus that currently lacks curative treatments. Lactoferrin (LF) is a naturally occurring non-toxic glycoprotein with broad-spectrum antiviral, immunomodulatory and anti-inflammatory effects. In this study, we assessed the potential of LF in the prevention of SARS-CoV-...

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Bibliographic Details

Published in:	Nutrients 2021-01, Vol.13 (2), p.328
Main Authors:	Salaris, Claudio, Scarpa, Melania, Elli, Marina, Bertolini, Alice, Guglielmetti, Simone, Pregliasco, Fabrizio, Blandizzi, Corrado, Brun, Paola, Castagliuolo, Ignazio
Format:	Article
Language:	eng
Subjects:	Analysis Animals Antibiotics Antibodies Antiviral agents Antiviral Agents - pharmacology antiviral immunity Caco-2 Cells Cell culture Chlorocebus aethiops Coronaviruses COVID-19 COVID-19 - immunology COVID-19 - pathology COVID-19 - prevention & control Cytokines Disease transmission Epithelial cells Gene expression Gene Expression Regulation - drug effects Gene Expression Regulation - immunology Genes Genomes Glycoproteins Health aspects Heparan sulfate Humans Immune response Immune system Immunity, Innate - drug effects Immunomodulation Infection Infections Inflammation Interferon regulatory factor 3 Interferon regulatory factor 7 Intestine Lactoferrin Lactoferrin - pharmacology Lactoferrins Pharmaceutical industry Plaque assay SARS-CoV-2 SARS-CoV-2 - immunology Scientific equipment and supplies industry Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Software Statistical analysis TLR3 protein TLR7 protein Toll-like receptors Vero Cells Viral diseases Viruses
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