Treatment of lichen planopilaris with mycophenolate mofetil

Mycophenolate mofetil (MMF) is an immunosuppressive drug that has recently been used to treat autoimmune and inflammatory skin diseases. We report the first case of lichen planopilaris (LPP) successfully treated with MMF. The treatment of our patient demonstrates a novel therapeutic option for patie...

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Bibliographic Details
Published in:Dermatology online journal 2004, Vol.10 (1), p.24
Main Authors: Tursen, Umit, Api, Hale, Kaya, Tamer, Ikizoglu, Guliz
Format: Article
Language:English
Subjects:
Adult
Alopecia - etiology
Humans
Immunosuppressive Agents - pharmacology
Immunosuppressive Agents - therapeutic use
Lichen Planus - complications
Lichen Planus - drug therapy
Lichen Planus - immunology
Lichen Planus - pathology
Male
Mycophenolic Acid - analogs & derivatives
Mycophenolic Acid - pharmacology
Mycophenolic Acid - therapeutic use
Pruritus - etiology
Remission Induction
Scalp Dermatoses - complications
Scalp Dermatoses - drug therapy
Scalp Dermatoses - immunology
Scalp Dermatoses - pathology
T-Lymphocytes - drug effects
T-Lymphocytes - pathology
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Summary:Mycophenolate mofetil (MMF) is an immunosuppressive drug that has recently been used to treat autoimmune and inflammatory skin diseases. We report the first case of lichen planopilaris (LPP) successfully treated with MMF. The treatment of our patient demonstrates a novel therapeutic option for patients with LPP; MMF treatment may be preferable to azathioprine treatment because MMF has a safer adverse-effect profile. Larger studies must be performed to establish the risk-benefit ratio of various therapeutic dosages of MMF for these patients.
ISSN:1087-2108
1087-2108
DOI:10.5070/D38Z97B9JB