Mizaj as an Index in Persian Traditional Medicine Index Could Associate with Sensitivity to the Radiation

Background: The sensitivity to the radiation among human population depends on various parameters. This variation could lead to dissimilar outcome of radiotherapy in similar situations. Mizaj is a well-known term in Persian medicine that present an individualized medicine viewpoint. All of the peopl...

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Published in:Galen 2020-08, Vol.9
Main Authors: Ebrahimnejad Gorji, Kourosh, Asghari, Fatemeh, Mozaffarpour, Seyyed Ali, Shabestani Monfared, Ali, Zabihi, Ebrahim, Abedian, Zeinab, Shirafkan, Hoda, Niksirat, Fatemeh, Borzoueisileh, Sajad
Format: Article
Language:English
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Summary:Background: The sensitivity to the radiation among human population depends on various parameters. This variation could lead to dissimilar outcome of radiotherapy in similar situations. Mizaj is a well-known term in Persian medicine that present an individualized medicine viewpoint. All of the people will be categorized in cold, moderate, and warm Mizaj. In this study, we aimed to evaluate the possible association between Mizaj and radiosensitivity by comet assay. Materials and Methods: Peripheral blood sample of 30 healthy volunteers (10 cold, 11 moderate and nine warm Mizaj) were taken and divided into two identical parts. The first part was exposed to 4 Gy x-rays, and the second part was regarded as the sham control. Then, DNA damages of samples were evaluated by the neutral comet assay. Results: The results showed that the mean percentage of damaged cells, in all of the irradiated groups including A (warm), B (moderate) and C (cold) was significantly higher than the controls (P
ISSN:2588-2767
2322-2379
DOI:10.31661/gmj.v9i.1705