Isolation, Semi-Synthesis and Antifeedant Activity of Constituents from Derris scandens Benth

This work describes the semi-synthesis of derivatives from derris isoflavone-A (1), scandenin (2) and 6,8-diprenyl-4′,5,7-trihydroxy isoflavone (3) which are major constituents isolated from chloroform extract of Derris scandens Benth. All the semi-synthesized derivatives (4-11) were characterized b...

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Bibliographic Details
Published in:Asian journal of chemistry 2020-10, Vol.32 (10), p.2535-2540
Main Authors: Poorna, P., Ramakrishna, K., Appa Rao, M. Suri
Format: Article
Language:English
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Summary:This work describes the semi-synthesis of derivatives from derris isoflavone-A (1), scandenin (2) and 6,8-diprenyl-4′,5,7-trihydroxy isoflavone (3) which are major constituents isolated from chloroform extract of Derris scandens Benth. All the semi-synthesized derivatives (4-11) were characterized by NMR and mass spectroscopic techniques. All these derivatives are evaluated for their antifeedant activity in castor semilooper and tobacco caterpillar using a no-choice laboratory bioassay. The results demonstrated that scandenin (2), compounds 5, 7 and 10 have shown potent insecticidal activity.
ISSN:0970-7077
0975-427X
DOI:10.14233/ajchem.2020.22801