Comparative and Stability Analyses of 9- and 13-Oxo-octadecadienoic Acids in Various Species of Tomato

Peroxisome proliferator-activated receptor-α (PPARα) regulates lipid metabolism. We have reported that tomato fruit contains 9-Oxo-(10E,12E)-octadecadienoic acid (9-Oxo-(10E,12E)-ODA), a PPARα agonist. In this study, we found that various tomato samples contained 9-Oxo-(10E,12Z)-ODA and its 13-Oxo-O...

Full description

Saved in:
Bibliographic Details
Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2011, Vol.75 (8), p.1621-1624
Main Authors: TAKAHASHI, Haruya, KIM, Young-Il, HIRAI, Shizuka, GOTO, Tsuyoshi, OHYANE, Chie, TSUGANE, Taneaki, KONISHI, Chiaki, FUJII, Takashi, INAI, Shuji, IIJIMA, Yoko, AOKI, Koh, SHIBATA, Daisuke, TAKAHASHI, Nobuyuki, KAWADA, Teruo
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chromatography, Liquid
Drug Stability
Dyslipidemias - drug therapy
Dyslipidemias - physiopathology
Fatty Acids, Unsaturated - chemistry
Fatty Acids, Unsaturated - isolation & purification
Fatty Acids, Unsaturated - pharmacology
Fruit - chemistry
Fundamental and applied biological sciences. Psychology
Isomerism
Lipid Metabolism - drug effects
liquid chromatography/mass spectrometer (LC/MS)
Lycopersicon esculentum - chemistry
Magnetic Resonance Spectroscopy
Mass Spectrometry
peroxisome proliferator-activated receptor-α (PPARα)
PPAR alpha - agonists
PPAR alpha - metabolism
structural stability
tomato
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Peroxisome proliferator-activated receptor-α (PPARα) regulates lipid metabolism. We have reported that tomato fruit contains 9-Oxo-(10E,12E)-octadecadienoic acid (9-Oxo-(10E,12E)-ODA), a PPARα agonist. In this study, we found that various tomato samples contained 9-Oxo-(10E,12Z)-ODA and its 13-Oxo-ODA isomers. Furthermore, several isomers showed structural stability under hot and acidic conditions.
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.110254