Aortic elastic properties in patients with venous thromboembolism

Objectives The relationship between venous thrombosis (VT) and atherosclerosis is controversial in recent studies. Aortic elastic properties have a predictive value in detecting early stages of atherosclerosis. The aim of this study is to evaluate the relationship between aortic elastic properties a...

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Bibliographic Details
Published in:Phlebology 2010-10, Vol.25 (5), p.246-251
Main Authors: Duran, N E, Oğuz, E, Duran, I, Aykan, A Ç, Ertürk, E, Bayram, Z, Gürsoy, M O, Biteker, M, Karavelioğlu, Y, Kaya, H, Özkan, M
Format: Article
Language:English
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Summary:Objectives The relationship between venous thrombosis (VT) and atherosclerosis is controversial in recent studies. Aortic elastic properties have a predictive value in detecting early stages of atherosclerosis. The aim of this study is to evaluate the relationship between aortic elastic properties and VT. Methods Elastic properties of aorta in patients with spontaneous VT, without history of known cardiovascular disease and cardiovascular risk factors (n: 31), and in healthy subjects without cardiovascular risk factors (n: 30) were compared. Elastic properties of the aorta were assessed with transthoracic echocardiography. Results A significant increase in aortic stiffness index (6.5 ± 1.0 versus 6 ± 0.7, P = 0.03) and a significant decrease in aortic strain and aortic distensibility were found in patients with VT compared with healthy subjects (8.4 ± 7 versus 13 ± 8, P = 0.01, 4.9 ± 4.8 versus 6.5 ± 4.4, P = 0.03, respectively). Conclusions Elastic properties of aorta in patients with spontaneous VT were impaired. These results may support the role of endothelial dysfunction in the pathogenesis of VT.
ISSN:0268-3555
1758-1125
DOI:10.1258/phleb.2009.009040