Serum Bovine Immunoglobulin for Chemotherapy-Induced Gastrointestinal Mucositis

Cancer treatments including chemotherapy and radiotherapy treat cancer by targeting rapidly dividing cells. Although these forms of treatment damage rapidly dividing cancer cells, they are also toxic to the cells of the gastrointestinal tract, leading to inflammation of the mucosal layer (mucositis)...

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Bibliographic Details
Published in:American journal of hospice & palliative medicine 2018-05, Vol.35 (5), p.814-817
Main Authors: Arikapudi, Sowminya, Rashid, Saima, Al Almomani, Laith Adel, Treece, Jennifer, Baumrucker, Steven J.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Antineoplastic Agents - adverse effects
Female
Gastrointestinal Diseases - chemically induced
Gastrointestinal Diseases - drug therapy
Humans
Immunoglobulins - therapeutic use
Mucositis - chemically induced
Mucositis - drug therapy
Neoplasms - drug therapy
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Summary:Cancer treatments including chemotherapy and radiotherapy treat cancer by targeting rapidly dividing cells. Although these forms of treatment damage rapidly dividing cancer cells, they are also toxic to the cells of the gastrointestinal tract, leading to inflammation of the mucosal layer (mucositis) and causing nausea, vomiting, diarrhea, and abdominal pain. Improvement in symptoms may allow patients to have better performance status permitting ongoing treatment and possibly a better prognosis. This article describes the pathophysiology of chemotherapy-induced mucositis and includes 3 case reports of treatment of mucositis with serum bovine immunoglobulin.
ISSN:1049-9091
1938-2715
DOI:10.1177/1049909117735831