Patients at Intermediate Surgical Risk Undergoing Isolated Interventional or Surgical Aortic Valve Implantation for Severe Symptomatic Aortic Valve Stenosis: One-Year Results From the German Aortic Valve Registry

BACKGROUND:Transcatheter aortic valve replacement (TAVR) is increasingly being used for treatment of severe aortic valve stenosis in patients at intermediate risk for surgical aortic valve replacement (SAVR). Currently, real-world data comparing indications and clinical outcomes of patients at inter...

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Published in:Circulation (New York, N.Y.) N.Y.), 2018-12, Vol.138 (23), p.2611-2623
Main Authors: Werner, Nicolas, Zahn, Ralf, Beckmann, Andreas, Bauer, Timm, Bleiziffer, Sabine, Hamm, Christian W, Berkeredjian, Raffi, Berkowitsch, Alexander, Mohr, Friedrich W, Landwehr, Sandra, Katus, Hugo A, Harringer, Wolfgang, Ensminger, Stephan, Frerker, Christian, Möllmann, Helge, Walther, Thomas, Schneider, Steffen, Lange, Rüdiger
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Language:eng
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Summary:BACKGROUND:Transcatheter aortic valve replacement (TAVR) is increasingly being used for treatment of severe aortic valve stenosis in patients at intermediate risk for surgical aortic valve replacement (SAVR). Currently, real-world data comparing indications and clinical outcomes of patients at intermediate surgical risk undergoing isolated TAVR with those undergoing SAVR are scarce. METHODS:We compared clinical characteristics and outcomes of patients with intermediate surgical risk (Society of Thoracic Surgeons score 4%–8%) who underwent isolated TAVR or conventional SAVR within the prospective, all-comers German Aortic Valve Registry. RESULTS:A total of 7613 patients at intermediate surgical risk underwent isolated TAVR (n=6469) or SAVR (n=1144) at 92 sites in Germany between 2012 and 2014. Patients treated by TAVR were significantly older (82.5±5.0 versus 76.6±6.7 years, P
ISSN:0009-7322
1524-4539