Behavioural Measures in Frontotemporal Lobar Dementia and Other Dementias: The Utility of the Frontal Behavioural Inventory and the Neuropsychiatric Inventory in a National Cohort Study

Background: Distinguishing between patients with frontotemporal lobar dementia (FTLD) and other dementing illnesses remains a difficult task for many clinicians. In this study, we aimed to provide further evidence for the construct validity of the frontal behavioural inventory (FBI) and assess its u...

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Published in:Dementia and geriatric cognitive disorders 2007-01, Vol.23 (6), p.406-415
Main Authors: Blair, M., Kertesz, A., Davis-Faroque, N., Hsiung, G.-Y.R., Black, S.E., Bouchard, R.W., Gauthier, S., Guzman, D.A., Hogan, D.B., Rockwood, K., Feldman, H.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Analysis of Variance
Behavioral Symptoms - diagnosis
Behavioral Symptoms - etiology
Biological and medical sciences
Cohort Studies
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Dementia
Dementia - classification
Dementia - complications
Dementia - diagnosis
Diagnosis, Differential
Female
Frontal Lobe - physiopathology
Human viral diseases
Humans
Infectious diseases
Male
Medical sciences
Neurology
Neuropsychological Tests
Original Research Article
Personality Assessment
Reproducibility of Results
Sensitivity and Specificity
Vascular diseases and vascular malformations of the nervous system
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:Background: Distinguishing between patients with frontotemporal lobar dementia (FTLD) and other dementing illnesses remains a difficult task for many clinicians. In this study, we aimed to provide further evidence for the construct validity of the frontal behavioural inventory (FBI) and assess its utility in differentiating FTLD patients from other groups using data from the Canadian Collaborative Cohort of Related Dementias (ACCORD) study. Method: Baseline scores on the FBI and neuropsychiatric inventory (NPI) were compared among several clinical groups (n = 177). Results: The FBI discriminated a higher percentage of FTLD patients (>75% correct classification) from Alzheimer’s disease and other groups compared to the NPI (54.2%). Conclusion: This study provides good evidence for convergent validity between the FBI and NPI (r = 0.72), indicating that both measures capture similar psychopathology in this nationwide cohort.
ISSN:1420-8008
1421-9824
DOI:10.1159/000101908