Top-Down Control of Saccades as Part of a Generalized Model of Proactive Inhibitory Control

Centre de Neurosciences Cognitives, Unité Mixte de Recherche du Centre National de la Recherche Scientifique 5229, Université Claude Bernard, Lyon, Lyon, France ABSTRACT Lo and colleagues have recently described a recurrent network model of inhibitory control of saccadic eye movements based on neuro...

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Bibliographic Details
Published in:	Journal of neurophysiology 2009-11, Vol.102 (5), p.2578-2580
Main Author:	Ballanger, Benedicte
Format:	Article
Language:	eng
Subjects:	Animals Life Sciences Models, Neurological Nerve Net - physiology Neural Inhibition - physiology Neurons - physiology Saccades - physiology Superior Colliculi - cytology Superior Colliculi - physiology Visual Fields - physiology
Online Access:	Get full text
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Summary:	Centre de Neurosciences Cognitives, Unité Mixte de Recherche du Centre National de la Recherche Scientifique 5229, Université Claude Bernard, Lyon, Lyon, France ABSTRACT Lo and colleagues have recently described a recurrent network model of inhibitory control of saccadic eye movements based on neurophysiological observations in the frontal eye field (FEF) and superior colliculus (SC) of rhesus monkeys. This model emphasizes the proactive, inhibition-based, tonic neuronal activity that prevents the eye from moving in a countermanding paradigm. In this review I discuss the model with respect to existing literature that the authors did not mention, suggesting that proactive inhibitory control extends far beyond saccadic control and provides an interesting framework to interpret several attentional and movement disorders in humans. Address for reprint requests and other correspondence: B. Ballanger, Centre de Neurosciences Cognitives, CNRS UMR 5229, 67 Boulevard Pinel, 69675 Bron Cedex, France (E-mail: benedicte.ballanger{at}isc.cnrs.fr ).
ISSN:	0022-3077 1522-1598