Retinoids and cancer prevention

Prevention of cancer may soon be a possibility for people who, because of genetic disposition or environmental exposure to carcinogens, have a high risk for developing disease. One class of compounds being tested for their effectiveness in combatting cancer is the retinoids, which consists of the na...

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Bibliographic Details
Published in:Annual review of nutrition 1992, Vol.12 (1), p.161-181
Main Authors: HILL, D. L, GRUBBS, C. J
Format: Article
Language:English
Subjects:
Animals
Anticarcinogenic Agents - administration & dosage
Anticarcinogenic Agents - therapeutic use
Biological and medical sciences
bladder
boca
bouche
cabeza
control de enfermedades
controle de maladies
cou
disease control
enfermedades glandulas mamarias
foie
General aspects
head
higado
Humans
intestin
intestines
intestinos
leucemia
leucemie
leukaemia
linfoma
liver
lungs
lymphoma
lymphome
maladie des glandes mammaires
mammary gland diseases
Medical sciences
mouth
neck
neoplasmas
neoplasme
neoplasms
Neoplasms - prevention & control
Neoplasms, Experimental - prevention & control
pancreas
peau
pescuezo
piel animal
poumon
pulmones
Retinoids - administration & dosage
Retinoids - therapeutic use
retinol
skin
tete
Tumors
vejiga
vessie
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Description
Summary:Prevention of cancer may soon be a possibility for people who, because of genetic disposition or environmental exposure to carcinogens, have a high risk for developing disease. One class of compounds being tested for their effectiveness in combatting cancer is the retinoids, which consists of the natural vitamin A compounds (retinol, retinal, and all-trans-retenoic acid) and their derivatives. This review discusses the cancer preventive activity of retinoids in various tissues and organs.
ISSN:0199-9885
1545-4312
DOI:10.1146/annurev.nu.12.070192.001113