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Synthesis of acyl derivatives of L-tryptophan containing residues of anthranilic and oxalic acids

Oxamoyl derivatives of dipeptide, N -anthranoyl-L-tryptophan, were synthesized by acylation of L-tryptophan methyl ester hydrochloride with 3,1-benzoxazinone derivatives. A one-stage procedure was developed for the synthesis of esters of N -[2-( N ′-R-amidooxalyl)aminobenzoyl]-L-tryptophan.

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Bibliographic Details
Published in:Russian journal of organic chemistry 2008-05, Vol.44 (5), p.693-696
Main Authors: Shemchuk, L. A., Chernykh, V. P., Red’kin, R. G.
Format: Article
Language:English
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Summary:Oxamoyl derivatives of dipeptide, N -anthranoyl-L-tryptophan, were synthesized by acylation of L-tryptophan methyl ester hydrochloride with 3,1-benzoxazinone derivatives. A one-stage procedure was developed for the synthesis of esters of N -[2-( N ′-R-amidooxalyl)aminobenzoyl]-L-tryptophan.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428008050096