Activity of the HIV-1 Attachment Inhibitor BMS-626529, the Active Component of the Prodrug BMS-663068, against CD4-Independent Viruses and HIV-1 Envelopes Resistant to Other Entry Inhibitors

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Published in:Antimicrobial Agents and Chemotherapy 2013-09, Vol.57 (9), p.4172-4180
Main Authors: ZHUFANG LI, NANNAN ZHOU, YONGNIAN SUN, RAY, Neelanjana, LATAILLADE, Max, HANNA, George J, KRYSTAL, Mark
Format: Article
Language:English
Subjects:
Anti-HIV Agents
Anti-HIV Agents - pharmacology
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antibodies, Monoclonal - pharmacology
Antiviral Agents
Biological and medical sciences
CCR5 protein
CCR5 Receptor Antagonists
CD4 Antigens - metabolism
Cyclohexanes - pharmacology
Drug Resistance, Viral - drug effects
Enfuvirtide
HEK293 Cells
HIV Envelope Protein gp120 - metabolism
HIV Envelope Protein gp41 - pharmacology
HIV-1
HIV-1 - drug effects
HIV-1 - growth & development
HIV-1 - metabolism
Human immunodeficiency virus 1
Human viral diseases
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infectious diseases
Maraviroc
Medical sciences
Organophosphates - metabolism
Organophosphates - pharmacology
Peptide Fragments - pharmacology
Pharmacology. Drug treatments
Piperazines
Piperazines - metabolism
Piperazines - pharmacology
Prodrugs - metabolism
Prodrugs - pharmacology
Receptors, CCR5 - metabolism
Receptors, CXCR4
Receptors, CXCR4 - antagonists & inhibitors
Receptors, CXCR4 - metabolism
Receptors, Virus
Receptors, Virus - antagonists & inhibitors
Receptors, Virus - metabolism
Triazoles
Triazoles - pharmacology
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Virus Internalization
Virus Internalization - drug effects
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.00513-13