Two-week schedule of hypofractionated radiotherapy as a local salvage treatment for small hepatocellular carcinoma

Background and Aim In cases of small hepatocellular carcinoma (HCC) where established curative treatment cannot be applied, stereotactic body radiotherapy (SBRT) has been used as a non‐invasive alternative treatment modality. However, short‐course SBRT may not be safe if the tumor is located around...

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Bibliographic Details
Published in:Journal of gastroenterology and hepatology 2013-10, Vol.28 (10), p.1638-1642
Main Authors: Park, Jin-hong, Yoon, Sang Min, Lim, Young-Suk, Kim, So Yeon, Shim, Ju Hyun, Kim, Kang Mo, Lee, Han Chu, Cho, Byungchul, Park, Geumju, Kim, Jong Hoon
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Carcinoma, Hepatocellular - mortality
Carcinoma, Hepatocellular - radiotherapy
Dose Fractionation
Female
hepatocellular carcinoma
Humans
hypofractionated radiotherapy
Liver Neoplasms - mortality
Liver Neoplasms - radiotherapy
local control
Male
Middle Aged
Neoplasm Recurrence, Local
Radiosurgery
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted - methods
Radiotherapy Planning, Computer-Assisted - mortality
salvage
Salvage Therapy
Survival Rate
Time Factors
Treatment Outcome
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Summary:Background and Aim In cases of small hepatocellular carcinoma (HCC) where established curative treatment cannot be applied, stereotactic body radiotherapy (SBRT) has been used as a non‐invasive alternative treatment modality. However, short‐course SBRT may not be safe if the tumor is located around a critical normal organ. Therefore, we applied hypofractionated radiotherapy for these tumors and evaluated outcomes of this treatment. Methods Between December 2008 and August 2011, 26 patients (28 lesions) with HCC were treated with hypofractionated radiotherapy. Inclusion criteria were HCC not suitable for surgery or other local ablative therapy, a tumor size
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.12249