Designing a High-Sensitivity Dual-Band Nano-Biosensor Based on Petahertz MTMs to Provide a Perfect Absorber for Early-Stage Nonmelanoma Skin Cancer Diagnostic

The purpose of this study is the development of a novel high-performance low-petahertz (PHz) biosensor for nonmelanoma skin cancer (NMSC) diagnosis. The presented device is designed to work within a microwave imaging (MWI) regime, which is a promising alternative to conventional diagnostic methods s...

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Bibliographic Details
Published in:IEEE sensors journal 2024-06, Vol.24 (11), p.18418-18427
Main Authors: Hamza, Musa N., Tariqul Islam, Mohammad, Lavadiya, Sunil, Koziel, Slawomir, Ud Din, Iftikhar, Cavalcante de Souza Sanches, Bruno
Format: Article
Language:English
Subjects:
Absorbers
Absorption
Biomarkers
Biosensors
Cancer
cancer detection
Diagnosis
Diagnostic systems
Figure of merit
Image resolution
Medical imaging
Metamaterials
metamaterials (MMTs)
perfect absorber
Q factors
Sensitivity
Signal to noise ratio
Skin cancer
Terahertz communications
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Summary:The purpose of this study is the development of a novel high-performance low-petahertz (PHz) biosensor for nonmelanoma skin cancer (NMSC) diagnosis. The presented device is designed to work within a microwave imaging (MWI) regime, which is a promising alternative to conventional diagnostic methods such as visual examination, dermoscopy, and biopsy. The suggested biosensor incorporates a dual-band perfect absorber (operating bands at 0.909 and 1.215 PHz) constructed using aluminum layers separated by a dielectric material. Numerical studies confirm its suitability for NMSC diagnosis, enabling discrimination between healthy and cancerous skin tissues and precise visualization of affected areas. Compared to existing THz devices, the proposed biosensor offers improved sensitivity, a smaller size, and enhanced resolution, attributed partially to the transition to the PHz band. Moreover, our research highlights the potential of PHz spectroscopy for biomarker detection, advancing noninvasive MWI techniques for NMSC and other skin cancers. The proposed biosensor boasts higher sensitivity, figure of merit (FOM), and quality factor (Q-factor), while its insensitivity to polarization angle ensures superior signal-to-noise ratio and high-resolution imaging, instilling confidence in specialists.
ISSN:1530-437X
1558-1748
DOI:10.1109/JSEN.2024.3391347