(145) VITAMIN D DEFICIENCY IS ASSOCIATED WITH SEXUAL FUNCTION IMPAIRMENT: FINDINGS FROM A CROSS SECTIONAL STUDY

Abstract Objectives Vitamin D (vitD) is an antioxidant molecule involved in endothelial protection. Previous studies have investigated the association between vitD and erectile dysfunction (ED) with conflicting findings. We aimed to investigate the association between vitD levels and erectile functi...

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Published in:Journal of sexual medicine 2023-07, Vol.20 (Supplement_4)
Main Authors: Dr. Luca, Boeri, Dr. Edoardo, Pozzi, Dr. Federico, Belladelli, Dr. Giuseppe, Fallara, Dr. Simone, Cilio, Dr. Francesco, Lanzaro, Dr. Alessandro, Bertini, Dr. Luigi, Candela, Massimiliano, Raffo, Fausto, Negri, Alessia, d'Arma, Ludovica, Cella, Margherita, Fanton, Dr. Christian, Corsini, Dr. Paolo, Capogrosso, Prof. Francesco, Montorsi, Prof. Andrea, Salonia
Format: Article
Language:English
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Summary:Abstract Objectives Vitamin D (vitD) is an antioxidant molecule involved in endothelial protection. Previous studies have investigated the association between vitD and erectile dysfunction (ED) with conflicting findings. We aimed to investigate the association between vitD levels and erectile function in a cohort of men seeking medical help for ED as their primary compliant. Methods Data from 540 men were analyzed. Comorbidities were scored with the Charlson Comorbidity Index (CCI). Patients completed the International Index of Erectile Function (IIEF) and the Beck Inventory for Depression (BDI). Circulating hormones and VitD levels were measured in every patient [deficiency for vitD was defined as 30 ng/ml (Group C)]. Descriptive statistics and linear regression models tested the association between clinical variables and sexual functioning. Results Overall, 211 (39.1%), 197 (36.5%) and 132 (24.4%) patients were in group A, B and C, respectively. Groups were similar for age, BMI, CCI, sex steroids, smoking and alcohol habits. IIEF-EF domain score was lower in group A compared to group B (p
ISSN:1743-6095
1743-6109
DOI:10.1093/jsxmed/qdad062.012