Verification of the impact of the improvement and worsening of anemia after discharge of heart failure on cardiorenal nutrition and the prognosis of HFpEF from the PURSUIT-HFpEF registry

Abstract Background Anemia has been reported as poor prognostic factor on heart failure with preserved ejection fraction (HFpEF) in past reports. Aim The aim of this study is to evaluate the impact of the improvement or worsening of anemia from discharge of heart failure to 1 year after discharge on...

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Published in:European heart journal 2022-10, Vol.43 (Supplement_2)
Main Authors: Kitao, T, Tamaki, S, Yano, M, Hayashi, T, Yamada, T, Yasumura, Y, Hikoso, S, Sotomi, Y, Sakata, Y
Format: Article
Language:English
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Summary:Abstract Background Anemia has been reported as poor prognostic factor on heart failure with preserved ejection fraction (HFpEF) in past reports. Aim The aim of this study is to evaluate the impact of the improvement or worsening of anemia from discharge of heart failure to 1 year after discharge on the prognosis of HFpEF and evaluate the effects of those changes on cardiorenal nutrition. Objective The subjects were 547 PURSUIT-HFpEF enrolled patients whose hemoglobin (Hb) and Controlling Nutrition Status (CONUT) were evaluated both at discharge and 1 year after discharge. Method First, 547 cases were divided into two groups, anemia (n=218) and non anemia (n=329), by Hb at discharge. Next, the anemia group (n=218) at discharge was divided into anemia group (G1, n=113) and non anemia group (G2, n=105) by Hb at 1 year later. Similarly, the non anemia group (n=329) at discharge was divided into anemia group (G3, n=66) and no anemia group (G4, n=263). Major Adverse Cardiovascular Event (MACE) was defined as composite of all-cause death, heart failure readmission, and cerebrovascular events. Anemia was defined as Hb
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehac544.1051