Role of right ventricular free wall longitudinal strain in prediction outcome in patients with cardiac sarcoidosis

Abstract Introduction Right ventricular free wall longitudinal strain (RVFWLS) is a sensitive tool for right ventricular (RV) function assessment. Furthermore, it shows incremental prognostic role in various cardiac diseases. RV involvement is frequently observed along with left ventricular (LV) inv...

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Bibliographic Details
Published in:European heart journal 2021-10, Vol.42 (Supplement_1)
Main Authors: Albakaa, N, Sato, K, Iida, N, Yamamoto, M, Machino, T, Ishizu, T, Ieda, M
Format: Article
Language:English
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Summary:Abstract Introduction Right ventricular free wall longitudinal strain (RVFWLS) is a sensitive tool for right ventricular (RV) function assessment. Furthermore, it shows incremental prognostic role in various cardiac diseases. RV involvement is frequently observed along with left ventricular (LV) involvement in cardiac sarcoidosis (CS) patients, while its impact on outcome is unclear. Purpose The aim of this study is to investigate the association between RV dysfunction detected by RVFWLS and cardiovascular event in patients with CS. Methods We retrospectively evaluated 51 patients with CS who were treated with prednisone from 2012 through 2020. Diagnosis of CS was made according to the Japanese Circulation Society diagnostic criteria. We evaluated RVFWLS at baseline using vender-independent software. We considered major adverse cardiovascular event (MACE: ventricular arrhythmia, heart failure hospitalization) to be the primary outcome. Results Mean age of the study population was 63±11 years, and 61% were female. At baseline, 25 patients (49%) had reduced left ventricular (LV) ejection fraction (EF) (
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehab724.1809