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Comparison of effective regurgitant orifice area by the PISA method and tricuspid coaptation gap measurement to identify very severe tricuspid regurgitation and stratify mortality risk

Abstract Funding Acknowledgements Type of funding sources: None. Background Various definitions of very severe (VS) tricuspid regurgitation (TR) have been proposed based on the effective regurgitant orifice area (EROA) or tricuspid coaptation gap (TCG). Because of the inherent limitations associated...

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Bibliographic Details
Published in:European heart journal cardiovascular imaging 2023-06, Vol.24 (Supplement_1)
Main Authors: Bohbot, Y, Tordjman, L, Dreyfus, J, Le Tourneau, T, Lavie Badie, Y, Selto, C, Elegamandji, B, L'official, G, Fraix, A, Aghezzaf, S, Turgeon, P Y, Enriquez Sarano, M, Coisne, A, Donal, E, Tribouilloy, C
Format: Article
Language:English
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Summary:Abstract Funding Acknowledgements Type of funding sources: None. Background Various definitions of very severe (VS) tricuspid regurgitation (TR) have been proposed based on the effective regurgitant orifice area (EROA) or tricuspid coaptation gap (TCG). Because of the inherent limitations associated with the EROA, we hypothesized that the TCG would be more suitable for defining VSTR and predicting outcomes. Purpose To compare EROA and TCG for outcome prediction in patients with severe TR Methods In this French multicentre retrospective study, we included 606 patients with ≥ moderate-to-severe isolated TR (without structural valve disease or an overt cardiac cause) according to the recommendations of the European Association of Cardiovascular Imaging. Patients were further stratified into VSTR according to the EROA (≥60 mm²) and then according to the TCG (≥10 mm). The primary endpoint was all-cause mortality and the secondary endpoint was cardiovascular mortality. Results The relationship between the EROA and TCG was poor (R²=0.21), especially when the size of the defect was large. Four-year survival was comparable between patients with an EROA
ISSN:2047-2404
2047-2412
DOI:10.1093/ehjci/jead119.009