Effects of system geometry and other physical factors on photon sensitivity of high-resolution positron emission tomography

We are studying two new detector technologies that directly measure the three-dimensional coordinates of 511 keV photon interactions for high-resolution positron emission tomography (PET) systems designed for small animal and breast imaging. These detectors are based on (1) lutetium oxyorthosilicate...

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Bibliographic Details
Published in:	Physics in medicine & biology 2007-07, Vol.52 (13), p.3753-3772
Main Authors:	Habte, F, Foudray, A M K, Olcott, P D, Levin, C S
Format:	Article
Language:	eng
Subjects:	Animals Cadmium Compounds - chemistry Computer Simulation Crystallization Equipment Design Image Processing, Computer-Assisted Lutetium - chemistry Monte Carlo Method Photons Positron-Emission Tomography - instrumentation Positron-Emission Tomography - methods Sensitivity and Specificity Silicates - chemistry Tellurium - chemistry Transducers Zinc - chemistry
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Summary:	We are studying two new detector technologies that directly measure the three-dimensional coordinates of 511 keV photon interactions for high-resolution positron emission tomography (PET) systems designed for small animal and breast imaging. These detectors are based on (1) lutetium oxyorthosilicate (LSO) scintillation crystal arrays coupled to position-sensitive avalanche photodiodes (PSAPD) and (2) cadmium zinc telluride (CZT). The detectors have excellent measured 511 keV photon energy resolutions (
ISSN:	0031-9155 1361-6560