Total serum bilirubinemia and intensity of sulfur mustard exposure in Iranian chemical victims 20 years after exposure

Sulfur mustard has various toxic effects. Some of the complications due to sulfur mustard toxicity are well known and some are unclear. In this study, serum total bilirubin and some hematologic parameters were evaluated in populations exposed to different doses of sulfur mustard. The sulfur mustard-...

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Bibliographic Details
Published in:Toxin reviews 2009-02, Vol.28 (1), p.44-47
Main Authors: Nadoushan, Mohammad Reza Jalali, Ghazanfari, Tooba, Yaraee, Roya, Mahdavi, Mohammad Reza Vaez, Soroush, Mohammad Reza, Moaiedmohseni, Sakine, Ghasemi, Hassan, Shams, Jalaleddin, Fallahi, Faramarz, Ardestani, Sussan K., Malekpour, Basir, Sha-Ali, Akbar, Hassan, Zuhair Mohammad, Faghihzadeh, Soghrat
Format: Article
Language:English
Subjects:
bilirubin
hemolysis
liver function tests
Sardasht-Iran Cohort Study
Sulfur mustard
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Summary:Sulfur mustard has various toxic effects. Some of the complications due to sulfur mustard toxicity are well known and some are unclear. In this study, serum total bilirubin and some hematologic parameters were evaluated in populations exposed to different doses of sulfur mustard. The sulfur mustard-exposed victims from Sardasht-Iran were divided into two groups 20 years after exposure, based on hospitalization at the time of the exposure. Studied groups were hospitalized and not hospitalized (n = 169 and n = 203, respectively). Liver function tests including total serum bilirubin, direct bilirubin, SGOT, SGPT, ALP, and hematologic parameters composed of RBC count, hemoglobin, hematocrit, and RBC indexes were evaluated. Total counts for RBC, MCV and total serum bilirubin were significantly different between the two groups, but there was no statistically significant difference in direct bilirubin, SGOT, SGPT, ALP, hemoglobin, hematocrit, MCH, MCHC between the two groups.
ISSN:1556-9543
1556-9551
DOI:10.1080/15569540802689865