Clinical predictors of adverse cardiovascular events for acute pediatric drug exposures

Context: Risk factors for adverse cardiovascular events (ACVE) from drug exposures have been well-characterized in adults but not studied in children. The objective of the present study is to describe the incidence, characteristics, and risk factors for in-hospital ACVEs among pediatric emergency de...

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Bibliographic Details
Published in:Clinical toxicology (Philadelphia, Pa.) Pa.), 2020-03, Vol.58 (3), p.183-189
Main Authors: Carreiro, Stephanie, Miller, Simone, Wang, Bo, Wax, Paul, Campleman, Sharan, Manini, Alex F.
Format: Article
Language:English
Subjects:
Adolescent
adverse events
Age Factors
Analgesics, Non-Narcotic - poisoning
Antidepressive Agents - poisoning
Cardiotonic Agents - poisoning
cardiovascular
Cardiovascular Diseases - chemically induced
Cardiovascular Diseases - mortality
Child
Child, Preschool
Cholinergic Antagonists - poisoning
Drug Overdose - epidemiology
Drug Overdose - etiology
Drug Overdose - mortality
Emergency Service, Hospital - statistics & numerical data
Hospital Mortality
Humans
Hypnotics and Sedatives - poisoning
Infant
Infant, Newborn
Logistic Models
Male
opioid
Pediatrics
poisoning
Prospective Studies
Registries
Risk Factors
Treatment Outcome
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Summary:Context: Risk factors for adverse cardiovascular events (ACVE) from drug exposures have been well-characterized in adults but not studied in children. The objective of the present study is to describe the incidence, characteristics, and risk factors for in-hospital ACVEs among pediatric emergency department (ED) patients with acute drug exposures. Methods: This is a prospective cohort design evaluating patients in the Toxicology Investigators Consortium (ToxIC) Registry. Pediatric patients (age
ISSN:1556-3650
1556-9519
DOI:10.1080/15563650.2019.1634272