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Health care resource utilization and treatment variability in the care of patients with advanced or metastatic colorectal or gastric cancer

This study was designed to describe health care resource utilization (HCRU) of patients with metastatic colorectal cancer (CRC) or gastric cancer to test the hypothesis that greater treatment variability would be associated with increased HCRU. A retrospective observational study using Marketscan cl...

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Bibliographic Details
Published in:Journal of medical economics 2021-01, Vol.24 (1), p.930-938
Main Authors: Hess, Lisa M., Zhu, Yajun Emily, Fang, Yun, Liepa, Astra M.
Format: Article
Language:English
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Summary:This study was designed to describe health care resource utilization (HCRU) of patients with metastatic colorectal cancer (CRC) or gastric cancer to test the hypothesis that greater treatment variability would be associated with increased HCRU. A retrospective observational study using Marketscan claims data was conducted. Eligible patients had a first diagnosis of metastatic CRC or gastric cancer between 2004 and 2015 and must have received systemic anti-cancer therapy after diagnosis. Treatment variability was measured using the Herfindahl-Hirschman Index (HHI). HHI scores were stratified by quartile. HCRU variables were evaluated throughout the follow-up period and described by 6-month periods. Chi-square test was used for categorical variables and ANOVA for continuous variables. A total of 55,403 CRC and 9,073 gastric cancer patients were eligible. First-line HHI scores ranged from 0.1304-0.2778 for CRC and 0.0383-0.1778 for gastric cancer by state of residence. Statistically significant differences by HHI quartiles for HCRU in CRC included hospitalizations (p = 0.0003), ER visits (p 
ISSN:1369-6998
1941-837X
DOI:10.1080/13696998.2021.1958607