Occurrence of β-lactam and polyether ionophore antibiotics in surface water, urban wastewater, and sediment

The occurrence and fate of antibiotic compounds in the aquatic environment has been recognized as an emerging area of interest in environmental chemistry. An analytical method was developed and validated for determining β-lactam and polyether ionophore antibiotics in surface water, urban wastewater,...

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Bibliographic Details
Published in:Geosystem engineering 2015, 18(3), , pp.140-150
Main Authors: Cha, Jongmun, Yang, Shinwoo, Carlson, Kenneth H.
Format: Article
Language:English
Subjects:
antibiotics
polyether ionophores
sediment
surface water
urban wastewater
β-lactams
자원공학
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Summary:The occurrence and fate of antibiotic compounds in the aquatic environment has been recognized as an emerging area of interest in environmental chemistry. An analytical method was developed and validated for determining β-lactam and polyether ionophore antibiotics in surface water, urban wastewater, and sediment based on solid-phase extraction (SPE) and liquid chromatography-ion trap tandem mass spectrometry (LC-MS-MS). The average recovery of β-lactams and polyether ionophores from all the fortified samples was generally higher than 80% (except for amoxicillin and ampicillin). A total of 400 actual water and sediment samples were analysed using SPE-LC-MS-MS to evaluate the occurrence and fate of these antibiotic compounds in a river and a wastewater treatment plant in northern Colorado. Most samples were found to be negative for β-lactam compounds. In those samples with positive results, β-lactam compounds were found at 15-17 ng/L in influent wastewater samples, 9-11 ng/L in surface water samples, and 0.13-0.36 μg/kg in sediment samples. No β-lactam compounds were detected in any effluent wastewater samples. The β-lactams are expected to be easily eliminated in wastewater treatment plants due to the lability of the β-lactam ring towards chemical and microbial degradation. The average concentration of ionophores ranged 0.03-0.05 μg/L in surface water samples and 0.5-3.1 μg/kg in sediment samples. These results confirm that β-lactam and ionophore antibiotics are adsorbed by sediment.
ISSN:1226-9328
2166-3394
DOI:10.1080/12269328.2015.1010658