Antidiabetic (α-amylase and α-glucosidase) and anti-obesity (lipase) inhibitory activities of edible cassava (Manihot esculenta Crantz) as measured by in vitro gastrointestinal digestion: effects of phenolics and harvested time

Edible cassava leaves (Manihot esculenta) were consumed as vegetables for their bioactive compounds, however the effect of harvesting time on these bioactive compounds and their antidiabetic and anti-obesity inhibitory activities were scarcely reported in the literature. Phenolics from edible leaves...

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Bibliographic Details
Published in:International journal of food properties 2022-12, Vol.25 (1), p.492-508
Main Authors: Laya, Alphonse, Koubala, Benoît B., Negi, Pradeep S.
Format: Article
Language:English
Subjects:
antidiabetic
Antidiabetics
Bioactive compounds
Bound phenolic
Cassava
Diabetes
Diabetes mellitus (non-insulin dependent)
Digestion
Flavonoids
harvest time
In vitro gastrointestinal digestion
Lipase
Manihot esculenta
Obesity
Phenolic compounds
Saponins
type 2 diabetes
α-Amylase
α-Glucosidase
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Summary:Edible cassava leaves (Manihot esculenta) were consumed as vegetables for their bioactive compounds, however the effect of harvesting time on these bioactive compounds and their antidiabetic and anti-obesity inhibitory activities were scarcely reported in the literature. Phenolics from edible leaves harvested at different times were assessed using HPLC-DAD, and their antidiabetic and anti-obesity inhibitory activities were investigated before and after in vitro gastrointestinal digestion. The results showed a significant (P 
ISSN:1094-2912
1532-2386
DOI:10.1080/10942912.2022.2050256