Evaluation of health outcomes after the implementation of rotational thromboelastometry in patients undergoing cardiac surgery

Viscoelastic tests (rotational thromboelastometry, ROTEM ® ), together with the implementation of a specific algorithm for coagulation management in cardiac surgery, enable perioperative coagulopathy to be better controlled. Retrospective cohort study including 675 patients who underwent cardiac sur...

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Published in:Scandinavian journal of clinical and laboratory investigation 2022-04, Vol.82 (2), p.143-149
Main Authors: Rodríguez-Martín, Isabel, Sánchez-Mora, Catalina, Fernández-López, Antonio R., González-Fernández, Francisco J., Téllez-Cantero, Juan Carlos, Blanco-Marquez, Verónica, García de la Borbolla, Mariano, Santos-Jiménez, Juan C., González-Rodríguez, Concepción, Garnacho-Montero, José, Sánchez-Margalet, Víctor
Format: Article
Language:English
Subjects:
Cardiac surgery
Cardiac Surgical Procedures - adverse effects
cardiopulmonary bypass
coagulopathy
hemostasis
Humans
Outcome Assessment, Health Care
Postoperative Hemorrhage - prevention & control
Retrospective Studies
ROTEM
Thrombelastography - methods
thromboelastometry
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Summary:Viscoelastic tests (rotational thromboelastometry, ROTEM ® ), together with the implementation of a specific algorithm for coagulation management in cardiac surgery, enable perioperative coagulopathy to be better controlled. Retrospective cohort study including 675 patients who underwent cardiac surgery with cardiopulmonary bypass. The incidence of allogeneic blood transfusions and clinical postoperative complications were analyzed before and after ROTEM ® implementation. Following viscoelastic testing and the implementation of a specific algorithm for coagulation management, the incidence of any allogeneic blood transfusion decreased (41.4% vs 31.9%, p = .026) during the perioperative period. In the group monitored with ROTEM ® , decreased incidence of transfusion was observed for packed red blood cells (31.3% vs 19.8%, p = .002), fresh frozen plasma (9.8% vs 3.8%, p = .008), prothrombin complex concentrate administration (0.9% vs 0.3%, p = .599) and activated recombinant factor VII (0.3% vs 0.0%, p = .603). Increased incidence was observed for platelet transfusion (4.8% vs 6.8%, p = .530) and fibrinogen concentrate (0.9% vs 3.5%, p = .066), tranexamic acid (0.0% vs 0.6%, p = .370) and protamine administration (0.6% vs 0.9%, p = .908). Similar results were observed in the postoperative period, but with a decreased incidence of platelet transfusion (4.8% vs 3.8%, p = .813). In addition, statistically significant reductions were detected in the incidence of postoperative bleeding (9.5% vs 5.3%, p = .037), surgical reexploration (6.0% vs 2.9%, p = .035), and length of Intensive Care Unit (ICU) stay (6.0 days vs 5.3 days, p = .026). The monitoring of hemostasis by ROTEM ® in cardiac surgery, was associated with decreased incidence of allogeneic blood transfusion, clinical hematologic postoperative complications and lengths of ICU stay.
ISSN:0036-5513
1502-7686
DOI:10.1080/00365513.2022.2034038