Leukocytosis caused by prostaglandin E1 in neonates

We conducted a retrospective study of neonatal leukocytosis induced by prostaglandin E1. Among 45 neonates with congenital heart disease, leukocyte counts increased during PGE1 infusion. We conclude that PGE1 infusion is a predictable cause of leukocytosis in newborns with congenital heart disease....

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Bibliographic Details
Published in:The Journal of pediatrics 2001-02, Vol.138 (2), p.263-265
Main Authors: Arav-Boger, Ravit, Baggett, Henry C., Spevak, Philip J., Willoughby, Rodney E.
Format: Article
Language:English
Subjects:
Alprostadil - adverse effects
Biological and medical sciences
Drug toxicity and drugs side effects treatment
Female
Heart Defects, Congenital - diet therapy
Humans
Infant, Newborn
Leukocyte Count
Leukocytosis - chemically induced
Medical sciences
Pharmacology. Drug treatments
Retrospective Studies
Toxicity: blood
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Summary:We conducted a retrospective study of neonatal leukocytosis induced by prostaglandin E1. Among 45 neonates with congenital heart disease, leukocyte counts increased during PGE1 infusion. We conclude that PGE1 infusion is a predictable cause of leukocytosis in newborns with congenital heart disease. (J Pediatr 2001;138:263-5)
ISSN:0022-3476
1097-6833
DOI:10.1067/mpd.2001.110304