Practical and Efficient Route to (S)-γ-Fluoroleucine

Abstract A practical and efficient route to (S)-γ-fluoroleucine was developed via compound 9. Introduction of the fluorine was achieved using N,N-diethylaminosulfur trifluoride (DAST) treatment on a tertiary alcohol 8.

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Bibliographic Details
Published in:Synlett 2005-05, Vol.2005 (8), p.1279-1280
Main Authors: Truong, Vouy Linh, Gauthier, Jacques Yves, Boyd, Michael, Roy, Bruno, Scheigetz, John
Format: Article
Language:English
Subjects:
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Description
Summary:Abstract A practical and efficient route to (S)-γ-fluoroleucine was developed via compound 9. Introduction of the fluorine was achieved using N,N-diethylaminosulfur trifluoride (DAST) treatment on a tertiary alcohol 8.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2005-868494