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Efficient Metal-Free Synthesis of Heterotriarylmethanes by 1,4-Addition of Benzofuran Azadienes

Abstract A novel and efficient method has been established for synthesizing a variety of heterotriarylmethanes with good yields by employing a metal-free self-coupling reaction of benzofuran azadienes. The involvement of t-BuONa is essential in this process. Remarkably, this technique boasts mild re...

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Bibliographic Details
Published in:Synlett 2024-08
Main Authors: Huang, Hong-Li, Li, Shan, Lv, Yong-Zheng, Shi, Ya-Qian, Liu, Chang-Bo, Peng, Zhongzhong, Gao, Fei
Format: Article
Language:English
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Summary:Abstract A novel and efficient method has been established for synthesizing a variety of heterotriarylmethanes with good yields by employing a metal-free self-coupling reaction of benzofuran azadienes. The involvement of t-BuONa is essential in this process. Remarkably, this technique boasts mild reaction conditions and exceptional compatibility with various functional groups, rendering it a versatile and invaluable asset in the realm of organic synthesis.
ISSN:0936-5214
1437-2096
DOI:10.1055/a-2370-6462