Surface-enhanced laser desorption/ionization mass spectrometry for rapid analysis of organic environmental pollutants by using polydopamine nanospheres as a substrate

Polydopamine nanospheres (PDA) were designed to serve as a new substrate for surface-enhanced desorption/ionization mass spectrometry (SELDI-MS). Compared with conventional organic matrices, the PDA substrate showed superior LDI performance for analyzing a wide variety of environmental pollutants, i...

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Bibliographic Details
Published in:Analyst (London) 2020-08, Vol.145 (16), p.5664-5669
Main Authors: Luo, Kailong, Yang, Baichuan, Guo, Wenjing, Sun, Qianqian, Dan, Ouyang, Lin, Zian, Cai, Zongwei
Format: Article
Language:English
Subjects:
Aromatic compounds
Bisphenols
Desorption
Estrogens
Ionization
Ions
Low concentrations
Mass spectrometry
Nanospheres
Perfluoro compounds
Pollutants
Polycyclic aromatic hydrocarbons
Scientific imaging
Spectroscopy
Substrates
Sulfonamides
Toxicity
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Summary:Polydopamine nanospheres (PDA) were designed to serve as a new substrate for surface-enhanced desorption/ionization mass spectrometry (SELDI-MS). Compared with conventional organic matrices, the PDA substrate showed superior LDI performance for analyzing a wide variety of environmental pollutants, including polycyclic aromatic hydrocarbons, bisphenols, benzophenones, sulfonamides, perfluorinated compounds and estrogens. Benzoapyrene was used to evaluate the ability of quantitative analysis and its corresponding limit of detection (LOD) of as low as 0.1 ng was achieved. High sensitivity and good reproducibility of PDA-based SELDI-MS allowed us to determine ultratrace PAHs in airborne particulate matters (PM 2.5 ), and the corresponding concentration of BaP in different PM 2.5 were 5.32, 8.97 and 9.79 ng m −3 . Significantly, PDA exhibits the characteristics of simple synthesis, low cost, non-toxicity and less matrix interference, which provides the possibility for the sensitive analysis of organic small molecule pollutants at low concentrations in complex environmental samples. Polydopamine nanospheres was designed to serve as a substrate for surface-enhanced desorption/ionization mass spectrometry, which showed superior LDI performance in the analysis of a variety of environmental pollutants.
ISSN:0003-2654
1364-5528
DOI:10.1039/d0an00895h