A red-emitting fluorescent probe for the detection of Hg 2+ in aqueous medium, living cells and organisms with a large Stokes shift

A red-emitting fluorescent probe has been developed for the selective and sensitive detection of Hg2+. With the addition of Hg2+, the solution of probe 1 displayed a remarkable fluorescence enhancement (102 fold) with λemmax = 625 nm and a large Stokes shift (150 nm). The detection limit of this pro...

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2018-07, Vol.16 (27), p.5036-5042
Main Authors: Yang, Lei, Su, Yuanan, Geng, Yani, Xiong, Haiqing, Han, Jinliang, Fang, Qian, Song, Xiangzhi
Format: Article
Language:English
Subjects:
Cell Survival
Color
Fluorescent Dyes - chemistry
HeLa Cells
Humans
Hydrogen-Ion Concentration
Kinetics
Mercury - analysis
Mercury - chemistry
Spectrometry, Fluorescence
Water - chemistry
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Summary:A red-emitting fluorescent probe has been developed for the selective and sensitive detection of Hg2+. With the addition of Hg2+, the solution of probe 1 displayed a remarkable fluorescence enhancement (102 fold) with λemmax = 625 nm and a large Stokes shift (150 nm). The detection limit of this probe was as low as 7.1 nM based on S/N = 3. This probe exhibited a good performance in detecting Hg2+ in real water samples, living cells and organisms.
ISSN:1477-0520
1477-0539
DOI:10.1039/C8OB00831K