Structure−Activity Relationship Studies Leading to the Identification of (2 E )-3-[l-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-l H -indol-7-yl]- N -[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide (DG-041), a Potent and Selective Prostanoid EP3 Receptor Antagonist, as a Novel Antiplatelet Agent That Does Not Prolong Bleeding

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Bibliographic Details
Published in:Journal of medicinal chemistry 2010-01, Vol.53 (1), p.18-36
Main Authors: Singh, Jasbir, Zeller, Wayne, Zhou, Nian, Hategan, Georgeta, Mishra, Rama K., Polozov, Alex, Yu, Peng, Onua, Emmanuel, Zhang, Jun, Ramírez, José L., Sigthorsson, Gudmundur, Thorsteinnsdottir, Margret, Kiselyov, Alex. S., Zembower, David E., Andrésson, Thorkell, Gurney, Mark E.
Format: Article
Language:English
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ISSN:0022-2623
1520-4804
DOI:10.1021/jm9005912